Vanillyl Mandelic Acid, Urine Test

What is the Vanillyl Mandelic Acid, Urine Test? Why is the test done? Everything around this, that you should know, in this post and of course our doctors are always there to help you. Just fill in your details in the form down below and we will answer all your questions for FREE!

What is a vanillyl mandelic acid (VMA)?

It is the breakdown product (metabolites) of epinephrine and norepinephrine. Epinephrine and norepinephrine are hormones called catecholamines.

Also Read: Norepinephrine Test
What is a vanillyl mandelic acid (VMA) urine test?

This test measures the amount of vanillyl mandelic acid in the urine.
This is typically a 24-hour urine test that helps in the screening of catecholamine-secreting tumours, such as ganglioneuroma and neuroblastoma.

What is the reference range of VMA?
  • Adults: < 6.8 mg/24 hr
  • Newborn: < 1 mg/24 hr
  • Infant: < 2mg/24 hr
  • Child: 1-3 mg/24 hr
  • Adolescent: 1.5 mg/24 hr
Why is a VMA test done?

This test is done to detect the tumour (neuroblastoma). This tumour is developed in the immature nerve cells in the adrenal glands, spinal cord, neck or chest. Neuroblastoma is commonly seen in young children.

If you have the symptoms of neuroblastoma in a child i.e.

  • Abnormal swelling in the abdomen, neck or chest
  • Bone pain
  • Painless, bluish lumps under the skin
  • Trouble breathing
  • Bulging eyes
  • Weakness in the arms or legs
  • Dark circles around the eyes

Other symptoms that are less seen in neuroblastoma are:

  • Fever
  • High blood pressure
  • Enlarged lymph nodes
  • Feeling tired
  • Droopy eyelids
  • Uncontrolled eye movements
What does a high VMA indicate?

The increased level of VMA indicates that you are suffering from such a condition.

  • Severe stress
  • Acute anxiety
  • Ganglioneuroma
  • Neuroblastoma
  • Ganglioblastoma
  • Pheochromocytoma (adrenal glands tumour)
What does a low VMA indicate?

The lower level of VMA is seen in such conditions like:

  • In diabetes
  • Parkinsonism
Also Read: Metanephrine Test

For more information, you can visit Testing .com and Medscape.

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