What is prothrombin?
Prothrombin is a vitamin K-dependent glycoprotein produced by the liver needed for fibrin clot formation.
Also Read: Bleeding Time
What is the prothrombin time (PT) test?
Prothrombin time measures the amount of time taken in seconds for clot formation.
What is the normal value of prothrombin time?
- Normal: 11-13 seconds
- Full anticoagulant therapy : > 1.5-2 times control value
- Critical value: >20 seconds
Why is the prothrombin time (PT) test done?
- This test is usually done in patients who are taking any blood-thinning medicines or warfarin) regularly to check if they are taking the dosage in the right way.
- The test is usually done if someone is scheduled for surgery it helps make sure blood is clotting normally to avoid complications during the procedure.
- Some people may need this test if they have bleeding or clotting disorder symptoms
Symptoms may include:
- Unexplained heavy bleeding
- The heavy menstrual period in women
- Leg pains or tenderness
- Redness or red streaks on the legs
- Rapid heartbeat.
What does high prothrombin time indicate?
It means that blood is clotting too slowly, which can be due to the following:
- Vitamin K deficiency
- Taking blood thinners regularly
- Low amount of protein that helps in clot formation
- Liver problem
What does low prothrombin time indicate?
It means that blood is clotting too quickly, which can be caused by:
- High intake of Vitamin K or Vitamin K supplements
- Hormonal therapy like birth control pills and oestrogen-containing medications.
