What is the Metanephrines Test, Urine? Why is the test done? Everything around this, that you should know, in this post and of course our doctors are always there to help you. Just fill in your details in the form down below and we will answer all your questions for FREE!
What is a metanephrine test?
This test measures the amount of metanephrine or normetanephrine present in the urine over a 24-hour period. It helps find out whether you have a tumor of the adrenal gland called pheochromocytomas or paraganglioma that releases an excess of metanephrines.
Also Read: Catecholamine Test
What are metanephrines?
These are made by the breakdown of catecholamines, which are made by the adrenal glands. They help your body fight stress. They include epinephrine, norepinephrine, and dopamine.
What is the role of the metanephrine test?
- It helps find out whether you have a tumor of the adrenal gland called pheochromocytomas or paraganglioma that releases an excess of metanephrines.
- It also helps to monitor the treatment of tumor
- It is also used to check for a recurrence of tumor
What is the normal level of metanephrines in the urine?
The units of measurement are mcg (micrograms). The normal range of urinary metanephrine is 24-96 mcg/24 hours.
If your urinary metanephrines or normetanephrine levels are greater than 400mcg over 24 hours, it is considered positive.
Why do I need to get tested?
You should get it done if you’re having any of the following symptoms:
- High blood pressure
- Headache
- Sweating
- Flushing of face
- Rapid heart rate (palpitations)
- Tremor
- Anxiety
- Chest pain
- Stomachache
- Fever
- Nausea, vomiting
- Heat intolerance
What does a high amount of metanephrines indicate?
The urinary metanephrines level twice the normal limit is generally considered positive. Elevated metanephrines in the blood indicate:
- You may have a tumor of the adrenal gland
- The treatment isn’t working or there is a recurrence of the tumor if you have been treated earlier.
This test is very sensitive and can be false positive too. It can be affected by:
- Stress
- Drugs
- Caffeine
- Smoking
- Antidepressants
- Other factors
