What is Adrenocorticotropic Hormone serum test (ACTH)? Why is the test done? Everything around this, that you should know, in this post and of course our doctors are always there to help you. Just fill in your details in the form down below and we will answer all your questions for FREE!
What is an Adrenocorticotrophic hormone serum test?
This is a test used to measure ACTH hormone in blood which is made by the pituitary gland. In return, it controls cortisol which is made by adrenal glands. Cortisol has various functions it is released during high BP, stress, infection, high blood sugar, etc.
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What are the other names for the test?
The other names for this test are:
- Corticotropin
- Adrenocorticotropic hormone blood test
What is the normal value for ACTH?
Its value at 8 am is between 10-60 pg/ml. What is the normal value for aldosterone in urine?
What is the test used for?
This test is done along with cortisol to diagnose various disorders of pituitary or adrenal gland. So, symptoms vary with high as well as low cortisol.
What are the health conditions that require this test?
The following health conditions require the test which are:
- Addison’s disease
- Cushing’s disease
- Hypopituitarism
- Cushing’s syndrome
What are the symptoms of high cortisol and thus high ACTH?
The symptoms include:
- Fat builds up in the shoulders
- Acne
- Fatigue
- Weight gain
- Stretch marks of pink or purple colour on the breast, thighs or abdomen
- Muscle weakness
- Increased body weakness
- Easy bruises
What are the symptoms of low cortisol and thus low ACTH?
The symptoms include:
- Diarrhoea
- Weight loss
- Vomiting
- Dizziness
- Nausea
- Skin darkening
- Fatigue
- Salt craving
- Pain in abdomen
What are the preparations that need to be done before the test?
Tests are usually done early in the morning as there is fluctuation in levels of cortisol throughout the day. Also, overnight fasting is required for the test.
How is the result interpretation done?
Results are often co-related with cortisol levels which are as follows:
- High cortisol with Low ACTH: Cushing’s syndrome or tumour in adrenal glands
- High cortisol with High ACTH: Cushing’s disease
- Low cortisol with High ACTH: Addison disease
- Low cortisol with Low ACTH: hypopituitarism
Is there any risk related to the test?
No, there is no risk except for some bruising at the site from where the blood sample has been taken, which usually resolves after some time.
