What is Farh’s Disease?
Fahr’s disease is a rare genetically dominant neurological disorder. In Fahr’s disease, calcium deposition occurs in various parts of the brain, resulting in progressive loss of motor and mental functions.
Does Fahr’s Disease Occur At Any Age?
Fahr’s disease can occur at any time in childhood or adult age but the typical age of onset is between 40 and 50 years of age.
What are the Causes Of Fahr’s disease?
A mutation has been reported in the gene encoding the type III sodium-dependent phosphate transporter 2 located on chromosome 8. Biochemical evidence shows that phosphate transport may be involved in the development of the disease.
What are the Signs and symptoms of Fahr’s disease?
• Poor motor function
• Dementia
• Headache
• Seizure
• Stiff limbs
• Poorly articulated speech
• Involuntary writhing movements
• Eye impairment
• Spastic paralysis
What Are Investigations Of Fahr’s disease?
• CT scan
• CSF examination
• Ellsworth Howard test
• Serology for toxoplasmosis
What Treatment is advised for Fahr’s disease?
• Treatment aims at symptomatic control.
• Genetic counselling may be helpful.
What is the Prognosis of Fahr’s disease?
The prognosis for Fahr’s disease varies and is difficult to predict.
What Are The Complications Of Fahr’s Disease?
• Retinitis pigmentosa
• Optic atrophy
• Demyelination
• Intracranial calcification
• Brain failure
• Parkinsonism
• Hypoparathyroidism
• Increased intraocular pressure
